Jefferson City, Missouri

HomeMissouriJefferson City

Email Staff Writer Staff Writer on LinkedIn Staff Writer on Twitter Staff Writer on Facebook
Staff Writer
Staff Writer
Contributor •

Gleevec Linked to Heart Failure

Comments Off

Jamie Sheller at Philadelphia Personal Injury Lawyer brings my attention to the news that Gleevec, a successful treatment for chronic myelogenous leukemia, had been linked to congestive heart failure in rare cases.

Ten CML patients treated with Gleevec at the M.D. Anderson Cancer Center in Houston developed congestive heart failure, although they had normal heart function when they began taking the drug. Studies in mice and in culture showed that the Abl tyrosine kinase protects cardiac cells from damage; when it is inhibited, heart cells die.

Read the full Gleevec story from MedPage today.